Article
Role of single nucleotide polymorphisms and haplotypes in BRCA1 in breast cancer: Czech case-control study.
Breast cancer research and treatment - 1 Jun 2007
Soucek P, Borovanova T, Pohlreich P, Kleibl Z, Novotny J
Abstract excerpt
We aimed at determining whether any association exists between six single nucleotide polymorphisms in breast cancer associated gene (BRCA1) and the risk of breast cancer. We constructed haplotypes and analyzed their importance as well. Clinico-pathological characteristics of breast cancer patients were included in the study to evaluate the prognostic impact of BRCA1 polymorphisms and haplotypes. Polymerase chain...
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