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Article

TGF-β1 functional polymorphisms: a review.

European cytokine network - 1 Nov 2016

Martelossi Cebinelli Guilherme Cesar, Paiva Trugilo Kleber, Badaró Garcia Stephanie, Brajão de Oliveira Karen

Abstract excerpt

Transforming Growth Factor β (TGF-β) is a multifunctional cytokine that plays a role in several biological processes. TGF-β1 is the most abundantly expressed isoform, associated with susceptibility to various diseases, and several polymorphisms have been described in the TGF-β1 gene structure, and some of them have been associated with functional implications. To date, eight single-nucleotide polymorphisms (SNPs)...

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Identifiers

PMID: 28396298
DOI: 10.1684/ecn.2016.0382

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