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Article

The TGFBR1*6A/9A polymorphism is not associated with differential risk of breast cancer.

Breast cancer research and treatment - 1 Jan 2010

Colleran Gabrielle, McInerney Niall, Rowan Andrew, Barclay Ella, Jones Angela M, Curran Catherine, Miller Nicola, Kerin Michael, Tomlinson Ian, Sawyer Elinor

Abstract excerpt

A polymorphic 9-bp deletion in exon 1 of TGFBR1 (TGFBR1*6A) has been identified as a low-penetrance cancer susceptibility allele. The strongest association in the initial studies was with breast cancer; however, these studies included patients with different types of cancer, including colon, cervical and breast carcinomas, with only a small proportion being breast cancer patients. In subsequent case-control...

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Source

Identifiers

PMID: 19390964
DOI: 10.1007/s10549-009-0395-0

Genes

TGFBR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

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The TGFBR1*6A/9A polymorphism is not associated with differential risk of breast cancer.PMID 19390964Read ↗

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Lack of an association between the TGFBR1*6A variant and colorectal cancer risk.Semantic proximity Read ↗

The TGFBR1*6A allele is not associated with susceptibility to colorectal cancer in a Spanish population: a case-control study.Semantic proximity Read ↗

TGFBR1*6A and cancer risk: a meta-analysis of seven case-control studies.Semantic proximity Read ↗

TGFBR1(*)6A and Int7G24A variants of transforming growth factor-beta receptor 1 in Swedish familial and sporadic breast cancer.Semantic proximity Read ↗

Meta-analysis of transforming growth factor β receptor I 6A/9A gene polymorphism and breast cancer risk: the picture remains murky.Semantic proximity Read ↗

The association of polymorphisms on TGFBR1 and colorectal cancer risk: a meta-analysis.Semantic proximity Read ↗

TGFBR1 variants TGFBR1(*)6A and Int7G24A are not associated with an increased familial colorectal cancer risk.Semantic proximity Read ↗

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TGFBR1*6A and cancer: a meta-analysis of 12 case-control studies.Semantic proximity Read ↗

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