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Article

MsbA-dependent translocation of lipids across the inner membrane of Escherichia coli.

The Journal of biological chemistry - 22 Oct 2004

Doerrler William T, Gibbons Henry S, Raetz Christian R H

Abstract excerpt

MsbA is an essential ABC transporter in Escherichia coli required for exporting newly synthesized lipids from the inner to the outer membrane. It remains uncertain whether or not MsbA catalyzes trans-bilayer lipid movement (i.e. flip-flop) within the inner membrane. We now show that newly synthesized lipid A accumulates on the cytoplasmic side of the inner membrane after shifting an E. coli msbA missense mutant...

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Identifiers

PMID: 15304478
DOI: 10.1074/jbc.M408106200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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