Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational analysis and properties of the msbA gene of Escherichia coli, coding for an essential ABC family transporter.

Molecular microbiology - 1 Jun 1996

Polissi A, Georgopoulos C

Abstract excerpt

The htrB gene was discovered because its insertional inactivation interfered with Escherichia coli growth and viability at temperatures above 32.5 degrees C, as a result of accumulation of phospholipids. The msbA gene was originally discovered because when cloned on a low-copy-number plasmid vector it was able to suppress the temperature-sensitive growth phenotype of an htrB null mutant as well as the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Binding Sites
Share to Cell Membrane

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Genetic Complementation Test

Share to Genetic Variation

Share to Membrane Proteins

Share to Mutation

Source

Identifiers

PMID: 8809774
DOI: 10.1111/j.1365-2958.1996.tb02642.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis and properties of the msbA gene of Escherichia coli, coding for an essential ABC family transporter.PMID 8809774Read ↗

The essential Escherichia coli msbA gene, a multicopy suppressor of null mutations in the htrB gene, is related to the universally conserved family of ATP-dependent translocators.Semantic proximity Read ↗

Function of Escherichia coli MsbA, an essential ABC family transporter, in lipid A and phospholipid biosynthesis.Semantic proximity Read ↗

Isolation and characterization of the Escherichia coli htrB gene, whose product is essential for bacterial viability above 33 degrees C in rich media.Semantic proximity Read ↗

The lethal phenotype caused by null mutations in the Escherichia coli htrB gene is suppressed by mutations in the accBC operon, encoding two subunits of acetyl coenzyme A carboxylase.Semantic proximity Read ↗

Characterization of the E506Q and H537A dysfunctional mutants in the E. coli ABC transporter MsbA.Semantic proximity Read ↗

Burkholderia cenocepacia Requires a Periplasmic HtrA Protease for Growth under Thermal and Osmotic Stress and for Survival In VivoSemantic proximity Read ↗

Function of the Escherichia coli msbB gene, a multicopy suppressor of htrB knockouts, in the acylation of lipid A. Acylation by MsbB follows laurate incorporation by HtrB.Semantic proximity Read ↗

MsbA-dependent translocation of lipids across the inner membrane of Escherichia coli.Semantic proximity Read ↗

Analysis of the Plasmid-Based ts Allele of PA0006 Reveals Its Function in Regulation of Cell Morphology and Biosynthesis of Core Lipopolysaccharide in Pseudomonas aeruginosa.Semantic proximity Read ↗

Complex phenotypes of null mutations in the htr genes, whose products are essential for Escherichia coli growth at elevated temperatures.Semantic proximity Read ↗

Mutations that alter the transmembrane signalling pathway in an ATP binding cassette (ABC) transporter.Semantic proximity Read ↗

Structure, Function, and Evolution of Bacterial ATP-Binding Cassette SystemsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.