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Article

Characterization of the E506Q and H537A dysfunctional mutants in the E. coli ABC transporter MsbA.

Biochemistry - 10 May 2011

Schultz Kathryn M, Merten Jacqueline A, Klug Candice S

Abstract excerpt

MsbA is a member of the ABC transporter superfamily that is specifically found in Gram-negative bacteria and is homologous to proteins involved in both bacterial and human drug resistance. The E506Q and H537A mutations have been introduced and used for crystallization of other members of the ABC transporter protein family, including BmrA and the ATPase domains MalK, HlyB-NBD, and MJ0796, but have not been...

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PMID: 21462989
DOI: 10.1021/bi101666p
PMCID: PMC3128438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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