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Article

Genetic and biochemical analyses of Pfh1 DNA helicase function in fission yeast.

Nucleic acids research - 1 Jan 2004

Ryu Gi-Hyuck, Tanaka Hiroyuki, Kim Do-Hyung, Kim Jeong-Hoon, Bae Sung-Ho, Kwon Young-Nam, Rhee Joon Shick, MacNeill Stuart A, Seo Yeon-Soo

Abstract excerpt

The Schizosaccharomyces pombe pfh1+ gene (PIF1 homolog) encodes an essential enzyme that has both DNA helicase and ATPase activities and is implicated in lagging strand DNA processing. Mutations in the pfh1+ gene suppress a temperature-sensitive allele of cdc24+, which encodes a protein that functions with Schizosaccharomyces pombe Dna2 in Okazaki fragment processing. In this study, we describe the enzymatic...

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Source

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Identifiers

PMID: 15302919
DOI: 10.1093/nar/gkh720
PMCID: PMC514361

Genes

PIF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic and biochemical analyses of Pfh1 DNA helicase function in fission yeast.PMID 15302919Read ↗

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