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Article

The fission yeast pfh1(+) gene encodes an essential 5' to 3' DNA helicase required for the completion of S-phase.

Nucleic acids research - 1 Nov 2002

Tanaka Hiroyuki, Ryu Gi-Hyuck, Seo Yeon-Soo, Tanaka Koichi, Okayama Hiroto, MacNeill Stuart A, Yuasa Yasuhito

Abstract excerpt

The Cdc24 protein plays an essential role in chromosomal DNA replication in the fission yeast Schizosaccharomyces pombe, most likely via its direct interaction with Dna2, a conserved endonuclease-helicase protein required for Okazaki fragment processing. To gain insights into Cdc24 function, we isolated cold-sensitive chromosomal suppressors of the temperature-sensitive cdc24-M38 allele. One of the...

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Identifiers

PMID: 12409464
DOI: 10.1093/nar/gkf590
PMCID: PMC135800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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