Article
Expression of PEG11 and PEG11AS transcripts in normal and callipyge sheep.
BMC biology - 6 Aug 2004
Bidwell Christopher A, Kramer Lauren N, Perkins Allison C, Hadfield Tracy S, Moody Diane E, Cockett Noelle E
Abstract excerpt
BACKGROUND: The callipyge mutation is located within an imprinted gene cluster on ovine chromosome 18. The callipyge trait exhibits polar overdominant inheritance due to the fact that only heterozygotes inheriting a mutant paternal allele (paternal heterozygotes) have a phenotype of muscle hypertrophy, reduced fat and a more compact skeleton. The mutation is a single A to G transition in an intergenic region that...
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