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Article

BEGAIN: a novel imprinted gene that generates paternally expressed transcripts in a tissue- and promoter-specific manner in sheep.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2005

Smit Maria A, Tordoir Xavier, Gyapay Gabor, Cockett Noelle E, Georges Michel, Charlier Carole

Abstract excerpt

In this article we describe the organization of the ovine BEGAIN gene, located 138 kb proximally from the imprinted DLK1 gene and 203 kb from the CLPG mutation that causes the callipyge phenotype. We have shown that in sheep BEGAIN is ubiquitously expressed, including in skeletal muscle, throughout development. We have identified four major BEGAIN transcripts resulting from a combination of alternate promoter...

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Topics

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle, Skeletal

Share to Muscular Diseases

Share to Regulatory Sequences, Nucleic Acid

Share to Sequence Homology, Nucleic Acid

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Source

Identifiers

PMID: 16261422
DOI: 10.1007/s00335-004-2415-z

Genes

BEGAIN
DLK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

BEGAIN: a novel imprinted gene that generates paternally expressed transcripts in a tissue- and promoter-specific manner in sheep.PMID 16261422Read ↗

Ectopic expression of DLK1 protein in skeletal muscle of padumnal heterozygotes causes the callipyge phenotype.Semantic proximity Read ↗

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The Imprinted Retrotransposon-Like Gene PEG11 (RTL1) Is Expressed as a Full-Length Protein in Skeletal Muscle from Callipyge SheepSemantic proximity Read ↗

Effect of DLK1 and RTL1 but not MEG3 or MEG8 on muscle gene expression in Callipyge lambs.Semantic proximity Read ↗

Genetic imprinting: conflict at the Callipyge locus.Semantic proximity Read ↗

Assessing the effect of the CLPG mutation on the microRNA catalog of skeletal muscle using high-throughput sequencing.Semantic proximity Read ↗

Postnatal changes in the expression of genes located in the callipyge region in sheep skeletal muscle.Semantic proximity Read ↗

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