Article
Differential expression of the GTL2 gene within the callipyge region of ovine chromosome 18.
Animal genetics - 1 Oct 2001
Bidwell C A, Shay T L, Georges M, Beever J E, Berghmans S, Cockett N E
Abstract excerpt
The inheritance pattern of the skeletal muscle hypertrophy phenotype caused by the callipyge gene has been characterized as polar overdominance. We hypothesized that this trait may be caused by a gain or loss of gene expression because of the reversible nature of the phenotype in paternal vs. maternal inheritance. Suppression subtraction cDNA probes were made from skeletal muscle mRNA of normal (NN) and callipyge...
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