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Article

Ectopic Expression of Retrotransposon-Derived PEG11/RTL1 Contributes to the Callipyge Muscular Hypertrophy.

PloS one - 1 Jan 2015

Xu Xuewen, Ectors Fabien, Davis Erica E, Pirottin Dimitri, Cheng Huijun, Farnir Frédéric, Hadfield Tracy, Cockett Noelle, Charlier Carole, Georges Michel, Takeda Haruko

Abstract excerpt

The callipyge phenotype is an ovine muscular hypertrophy characterized by polar overdominance: only heterozygous +Mat/CLPGPat animals receiving the CLPG mutation from their father express the phenotype. +Mat/CLPGPat animals are characterized by postnatal, ectopic expression of Delta-like 1 homologue (DLK1) and Paternally expressed gene 11/Retrotransposon-like 1 (PEG11/RTL1) proteins in skeletal muscle. We showed...

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Identifiers

PMID: 26474044
DOI: 10.1371/journal.pone.0140594
PMCID: PMC4608697

Genes

DLK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Ectopic Expression of Retrotransposon-Derived PEG11/RTL1 Contributes to the Callipyge Muscular Hypertrophy.PMID 26474044Read ↗

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