Article
Serine phosphorylation of mCRY1 and mCRY2 by mitogen-activated protein kinase.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Aug 2004
Sanada Kamon, Harada Yuko, Sakai Mihoko, Todo Takeshi, Fukada Yoshitaka
Abstract excerpt
The circadian oscillator is composed of a transcription/translation-based autoregulatory feedback loop in which Cryptochromes and Periods function as negative regulators for their own gene expression. Although post-translational modifications such as phosphorylation of these regulators appear crucial for circadian time-keeping mechanism, less is known about responsible protein kinases and their contribution to...
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