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Article

Disruption of hepatic C/EBPalpha results in impaired glucose tolerance and age-dependent hepatosteatosis.

The Journal of biological chemistry - 22 Oct 2004

Inoue Yusuke, Inoue Junko, Lambert Gilles, Yim Sun Hee, Gonzalez Frank J

Abstract excerpt

C/EBPalpha is highly expressed in liver and regulates many genes that are preferentially expressed in liver. Because C/EBPalpha-null mice die soon after birth, it is impossible to analyze the function of C/EBPalpha in the adult with this model. To address the function of C/EBPalpha in adult hepatocytes, liver-specific C/EBPalpha-null mice were produced using a floxed C/EBPalpha allele and the albumin-Cre...

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PMID: 15292250
DOI: 10.1074/jbc.M405177200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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