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Article

Generation of mice with a conditional allele for G6pc.

Genesis (New York, N.Y. : 2000) - 1 Sept 2009

Peng Wen-Tao, Pan Chi-Jiunn, Lee Eric J, Westphal Heiner, Chou Janice Y

Abstract excerpt

Glucose-6-phosphatase-alpha (G6Pase-alpha or G6PC) catalyzes the hydrolysis of glucose-6-phosphate to glucose and is a key enzyme in interprandial glucose homeostasis. Mutations in the human G6PC gene, expressed primarily in the liver, kidney, and intestine, cause glycogen storage disease Type Ia (GSD-Ia), an autosomal recessive disorder characterized by a disturbed glucose homeostasis. For better understanding...

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Identifiers

PMID: 19548314
DOI: 10.1002/dvg.20538
PMCID: PMC2755605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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