Article
ABCA7 in Alzheimer's Disease.
Molecular neurobiology - 1 Jan 2015
Zhao Qing-Fei, Yu Jin-Tai, Tan Meng-Shan, Tan Lan
Abstract excerpt
ATP-binding cassette A7 (ABCA7) gene has recently been identified as a strong genetic locus associated with late-onset Alzheimer's disease (LOAD) through genome-wide association studies (GWASs). ABCA7 is a member of the ATP-binding cassette (ABC) transporter gene superfamily, which codes for 49 ABC proteins, divided into 7 subfamilies (coded A-G). As a multispan transmembrane protein, ABCA7 is most abundantly...
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