Article
ABCA1 polymorphisms and Alzheimer's disease.
Neuroscience letters - 12 Apr 2007
Wavrant-De Vrièze Fabienne, Compton Danielle, Womick Meridith, Arepalli Sampath, Adighibe Omanma, Li Ling, Pérez-Tur Jordi, Hardy John
Abstract excerpt
In our search for genetic factors related to the development of Alzheimer's disease, we have genotyped 332 pedigrees for three coding polymorphisms in the ABCA1 gene, two of which are known to alter plasma cholesterol levels, as well as a non-coding polymorphism within the promoter. We show an apparent weak association of rs2230806 (p-value=0.01) with the disease in a sibpair series of Alzheimer's disease that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
