Article
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias.
Proceedings of the National Academy of Sciences of the United States of America - 10 Aug 2004
Calin George Adrian, Liu Chang-Gong, Sevignani Cinzia, Ferracin Manuela, Felli Nadia, Dumitru Calin Dan, Shimizu Masayoshi, Cimmino Amelia, Zupo Simona, Dono Mariella, Dell'Aquila Marie L, Alder Hansjuerg, Rassenti Laura, Kipps Thomas J, Bullrich Florencia, Negrini Massimo, Croce Carlo M
Abstract excerpt
Little is known about the expression levels or function of micro-RNAs (miRNAs) in normal and neoplastic cells, although it is becoming clear that miRNAs play important roles in the regulation of gene expression during development [Ambros, V. (2003) Cell 113, 673-676; McManus, M. T. (2003) Semin. Cancer Biol. 13, 253-258]. We now report the genomewide expression profiling of miRNAs in human B cell chronic...
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