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Article

Role of microRNAs in Chronic Lymphocytic Leukemia Pathogenesis

23 Sept 2019

Abstract excerpt

MicroRNAs (miRNAs) are a group of small endogenous non-coding RNAs involved in many cancers and various cellular processes such as cellular growth, DNA methylation, apoptosis, and differentiation. 13q14.3 chromosomal region contains miR-15 and miR-16 and deletion of this region is a commonly reported aberration in Chronic Lymphoblastic Leukemia (CLL), suggesting miRNAs involvement in CLL pathogenesis. MicroRNAs...

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PMID: 31544709
DOI: 10.2174/0929867326666190911114842

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