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Article

Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia

27 Feb 2007

Abstract excerpt

MicroRNAs (miRNAs) are a novel class of small noncoding RNAs that modulate the expression of genes at the posttranscriptional level. These small molecules have been shown to be involved in cancer, apoptosis, and cell metabolism. In the present study we provide an informative profile of the expression of miRNAs in primary chronic lymphocytic leukemia (CLL) cells using 2 independent and quantitative methods: miRNA...

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PMID: 17327404
DOI: 10.1182/blood-2006-12-062398

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