Article
microRNA and Chronic Lymphocytic Leukemia.
Advances in experimental medicine and biology - 1 Jan 2015
Giza Dana Elena, Calin George A
Abstract excerpt
Expression profiling of microRNAs identified important differences in microRNA expression between CLL samples and normal CD5+ B-cells. Researchers have first discussed the dual role of miRNAs working as tumor suppressors (inhibiting malignant potential) or as oncogenes (activating malignant potential) in CLL pathogenesis. Understanding the roles of miRNAs in leukemic cells brings information on a new layer of...
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