Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Further evidence of a combined effect of SERTPR and TPH on SSRIs response in mood disorders.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 Aug 2004

Serretti Alessandro, Cusin Cristina, Rossini David, Artioli Paola, Dotoli Danilo, Zanardi Raffaella

Abstract excerpt

We reported an independent association of the short variant of the serotonin transporter gene-linked polymorphic region (SERTPR) and tryptophan hydroxylase (TPH) genes with antidepressant response to selective serotonin reuptake inhibitors (SSRIs). The aim of the present study was to confirm the effect of the SERTPR and TPH gene variants on the SSRIs antidepressant activity in a new sample of major and bipolar...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Double-Blind Method
Share to Drug Therapy, Combination

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluvoxamine

Share to Mood Disorders

Share to Paroxetine

Share to Selective Serotonin Reuptake Inhibitors

Share to Serotonin Plasma Membrane Transport Proteins

Share to Tryptophan Hydroxylase

Source

Identifiers

PMID: 15274037
DOI: 10.1002/ajmg.b.30027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Further evidence of a combined effect of SERTPR and TPH on SSRIs response in mood disorders.PMID 15274037Read ↗

5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression.Semantic proximity Read ↗

Pharmacogenetics of selective serotonin reuptake inhibitors (SSRI): A serotonin reuptake transporter (SERT)-based approach.Semantic proximity Read ↗

Pooling pharmacogenetic studies on the serotonin transporter: a mega-analysis.Semantic proximity Read ↗

A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depressionSemantic proximity Read ↗

Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment.Semantic proximity Read ↗

The influence of 5-HTTLPR and STin2 polymorphisms in the serotonin transporter gene on treatment effect of selective serotonin reuptake inhibitors in depressive patients.Semantic proximity Read ↗

Serotonin transporter gene influences the time course of improvement of "core" depressive and somatic anxiety symptoms during treatment with SSRIs for recurrent mood disorders.Semantic proximity Read ↗

Increased risk for major depression associated with the short allele of the serotonin transporter promoter region (5-HTTLPR-S) and the CYP2C9*3 allele.Semantic proximity Read ↗

Antidepressant response and the serotonin transporter gene-linked polymorphic region.Semantic proximity Read ↗

Moderation of antidepressant response by the serotonin transporter gene.Semantic proximity Read ↗

Development and validation of a high-throughput screening method for two polymorphisms in the serotonin transporter gene.Semantic proximity Read ↗

Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.