Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased risk for major depression associated with the short allele of the serotonin transporter promoter region (5-HTTLPR-S) and the CYP2C9*3 allele.

Fundamental & clinical pharmacology - 1 Aug 2007

Dorado P, Peñas-Lledó E M, González A P, Cáceres M C, Cobaleda J, Llerena A

Abstract excerpt

In the present study, we aimed to analyze the potential relevance of the polymorphism in the promoter region of the serotonin transporter (SERT or 5-HTT) gene (5-HTTLPR) and the risk of suffering major depression (MDD) in a population of patients previously genotyped for CYP2C9. Seventy white Eur...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Hydroxylases
Share to Cytochrome P-450 CYP2C9
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Share to Risk Factors

Share to Serotonin Plasma Membrane Transport Proteins

Source

Identifiers

PMID: 17635185
DOI: 10.1111/j.1472-8206.2007.00501.x

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17635185-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased risk for major depression associated with the short allele of the serotonin transporter promoter region (5-HTTLPR-S) and the CYP2C9*3 allele.PMID 17635185Read ↗

Serotonin transporter polymorphism in Croatian patients with major depressive disorder.Semantic proximity Read ↗

CYP2C9 gene and susceptibility to major depressive disorder.Semantic proximity Read ↗

Variability in the serotonin transporter gene and increased risk for major depression with melancholia.Semantic proximity Read ↗

Serotonin transporter gene (5-HTT) polymorphism and major depressive disorder in patients in Bogotá, Colombia.Semantic proximity Read ↗

Serotonin-2A-receptor and -transporter polymorphisms: lack of association in patients with major depression.Semantic proximity Read ↗

Association between major depressive disorder and the -1438A/G polymorphism of the serotonin 2A receptor gene.Semantic proximity Read ↗

Further evidence of a combined effect of SERTPR and TPH on SSRIs response in mood disorders.Semantic proximity Read ↗

The serotonin transporter gene (5-HTT) variant and psychiatric disorders: review of current literature.Semantic proximity Read ↗

Genome-wide association data provide further support for an association between 5-HTTLPR and major depressive disorder.Semantic proximity Read ↗

Association of unipolar major depressive disorder with genes of the serotonergic and dopaminergic pathways.Semantic proximity Read ↗

Association between violent suicidal behavior and the low activity allele of the serotonin transporter gene.Semantic proximity Read ↗

Serotonin transporter gene polymorphisms, alcoholism, and suicidal behavior.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.