Article
A polymorphic CA repeat in the IGF-I gene is associated with gender-specific differences in body height, but has no effect on the secular trend in body height.
Clinical endocrinology - 1 Aug 2004
Rietveld I, Janssen J A M J L, van Rossum E F C, Houwing-Duistermaat J J, Rivadeneira F, Hofman A, Pols H A P, van Duijn C M, Lamberts S W J
Abstract excerpt
OBJECTIVE: A polymorphism near the promoter region of the IGF-I gene has been associated with serum IGF-I levels, age-related decline of serum IGF-I levels, body height, birth weight and intima media thickness in hypertensive subjects. DESIGN AND METHODS: We investigated the association between the length of the IGF-I alleles of this promoter polymorphism and IGF-I levels and body height. Furthermore, we...
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