Article
A polymorphism in the gene for IGF-I: functional properties and risk for type 2 diabetes and myocardial infarction.
Diabetes - 1 Mar 2001
Vaessen N, Heutink P, Janssen J A, Witteman J C, Testers L, Hofman A, Lamberts S W, Oostra B A, Pols H A, van Duijn C M
Abstract excerpt
Evidence is accumulating that low levels of IGF-I play a role in the pathogenesis of type 2 diabetes and cardiovascular diseases. We examined the role of a genetic polymorphism in the promoter region of the IGF-I gene in relation to circulating IGF-I levels and growth measured as body height, and we studied the relationship of this polymorphism with type 2 diabetes and myocardial infarction. The relation between...
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