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Article

Aging phenotype and its relationship with IGF-I gene promoter polymorphisms in elderly people living in Catalonia.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Jun 2011

Mora Mireia, Perales María José, Serra-Prat Mateu, Palomera Elisabet, Buquet Xavier, Oriola Josep, Puig-Domingo Manel

Abstract excerpt

OBJECTIVES: Genetic variations in the Insulin/IGF-I genes pathway have been related to longevity, dementia, metabolic diseases and cancer. The purpose of the present study was to investigate the 192 bp allele of IGF-I gene promoter and its relationship with metabolic syndrome (MS) components, mental and nutritional state, muscle strength and functional capacity in an aged Spanish population. DESIGN:...

Topics

Aged
Aging
Female
Heterozygote
Homozygote
Humans
Insulin-Like Growth Factor I
Male
Phenotype
Polymorphism, Genetic
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spain

Source

Identifiers

PMID: 21658593
DOI: 10.1016/j.ghir.2011.03.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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