Article
Aging phenotype and its relationship with IGF-I gene promoter polymorphisms in elderly people living in Catalonia.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Jun 2011
Mora Mireia, Perales María José, Serra-Prat Mateu, Palomera Elisabet, Buquet Xavier, Oriola Josep, Puig-Domingo Manel
Abstract excerpt
OBJECTIVES: Genetic variations in the Insulin/IGF-I genes pathway have been related to longevity, dementia, metabolic diseases and cancer. The purpose of the present study was to investigate the 192 bp allele of IGF-I gene promoter and its relationship with metabolic syndrome (MS) components, mental and nutritional state, muscle strength and functional capacity in an aged Spanish population. DESIGN:...
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