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Article

A polymorphism in the IGF-I gene influences the age-related decline in circulating total IGF-I levels.

European journal of endocrinology - 1 Feb 2003

Rietveld Ingrid, Janssen Joop A M J L, Hofman Albert, Pols Huibert A P, van Duijn Cornelia M, Lamberts Steven W J

Abstract excerpt

OBJECTIVE: Recent studies have demonstrated an association between a 192 bp polymorphism of the IGF-I gene and total IGF-I serum levels, birth weight, body height and the risk of developing diabetes and cardiovascular diseases later on in life. This IGF-I gene polymorphism in the promoter region of the IGF-I gene may directly influence the expression of IGF-I. In the present study we evaluated the role of this...

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PMID: 12590635
DOI: 10.1530/eje.0.1480171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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