Article
A variant of the IGF-I gene is associated with blood pressure but not with left heart dimensions at the age of 2 years: the Generation R Study.
European journal of endocrinology - 1 Sept 2008
van Houten Vera A A, Mook-Kanamori Dennis O, van Osch-Gevers Lennie, Steegers Eric A P, Hofman Albert, Moll Henriëtte A, van Duijn Cornelia M, Helbing Willem A, Hokken-Koelega Anita C S, Jaddoe Vincent W V
Abstract excerpt
BACKGROUND AND OBJECTIVE: A common variant of the IGF-I gene has been shown to be associated with cardiovascular disease in adulthood. The objective of this study was to examine whether this variant of the IGF-I gene is associated with blood pressure and left heart dimensions in early childhood. RESEARCH DESIGN AND METHODS: This study was embedded in the Generation R Study, a population-based prospective cohort...
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