Article
The future of association studies: gene-based analysis and replication.
American journal of human genetics - 1 Sept 2004
Neale Benjamin M, Sham Pak C
Abstract excerpt
Historically, association tests were limited to single variants, so that the allele was considered the basic unit for association testing. As marker density increases and indirect approaches are used to assess association through linkage disequilibrium, association is now frequently considered at the haplotypic level. We suggest that there are difficulties in replicating association findings at the...
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