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Article

The tumor necrosis factor alpha -308G>A polymorphism is associated with dementia in the oldest old.

Journal of the American Geriatrics Society - 1 Aug 2004

Bruunsgaard Helle, Benfield Thomas L, Andersen-Ranberg Karen, Hjelmborg Jacob v B, Pedersen Agnes N, Schroll Marianne, Pedersen Bente K, Jeune Bernard

Abstract excerpt

OBJECTIVES: To test the hypothesis that the tumor necrosis factor (TNF) -308 G>A promoter gene polymorphism is a risk factor in age-related dementia and longevity. DESIGN: A cross-sectional and a longitudinal study. SETTING: A population-based sample of Danish centenarians. PARTICIPANTS: One hundred-year-old Danes (n=122) from "The Longitudinal Study of Danish Centenarians." Octogenarians (n=174) and healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15271127
DOI: 10.1111/j.1532-5415.2004.52369.x

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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