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Article

-308(G/A) TNF-alpha gene polymorphism and risk of depression late in the life.

Archives of gerontology and geriatrics - 1 Jan 2009

Cerri A P, Arosio B, Viazzoli C, Confalonieri R, Teruzzi F, Annoni G

Abstract excerpt

The relationship between major depression (MD) and dementia in the elderly is still not clear, but it is certain that the immune system and in particular, pro-inflammatory cytokines, such as tumor necrosis factor (TNF)-alpha, play a key role in the mechanisms underlying the two neuro-psychiatric disorders. In our experience, the -308(G/A) single nucleotide polymorphism (SNP) in the TNF-alpha gene is associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19836613
DOI: 10.1016/j.archger.2009.09.009

Genes

TNF

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