Article
Tumor necrosis factor alpha polymorphism C-850T is not associated with Alzheimer's disease and vascular dementia in an Italian population.
Neuroscience letters - 26 Jun 2003
Terreni Liana, Fogliarino Sergio, Quadri Pierluigi, Ruggieri Rosa Maria, Piccoli Federico, Tettamanti Mauro, Lucca Ugo, Forloni Gianluigi
Abstract excerpt
A pathogenic role of inflammatory factors has been proposed both in Alzheimer's disease (AD) and vascular dementia (VD). A previous report indicated the presence of polymorphism C-850T of tumor necrosis factor (TNF) alpha as a genetic risk factor for VD and, associated with apolipoprotein E epsilon 4, for AD. We have assessed the association between TNF-alpha polymorphism and dementias in Italian populations of...
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