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Article

A population-based study in Ghana to investigate inter-individual variation in plasma t-PA and PAI-1.

Ethnicity & disease - 1 Jan 2007

Williams Scott M, Stocki Shelli, Jiang Lan, Brew Kwabena, Gordon Seth, Vaughan Douglas E, Brown Nancy J, Poku Kwabena A, Moore Jason H

Abstract excerpt

INTRODUCTION: Susceptibility to arterial thrombosis has a significant genetic component that is partly due to the expression of two proteins, tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1), that directly influence thrombus formation and degradation. We have initiated a large-scale population-based study to characterize the genetic architecture of plasma t-PA and PAI-1 in...

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PMID: 17985503

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A population-based study in Ghana to investigate inter-individual variation in plasma t-PA and PAI-1.PMID 17985503Read ↗

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