Article
The gender-specific role of polymorphisms from the fibrinolytic, renin-angiotensin, and bradykinin systems in determining plasma t-PA and PAI-1 levels.
Thrombosis and haemostasis - 1 Oct 2006
Asselbergs Folkert W, Williams Scott M, Hebert Patricia R, Coffey Christopher S, Hillege Hans L, Navis Gerjan, Vaughan Douglas E, van Gilst Wiek H, Moore Jason H
Abstract excerpt
Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) directly influence thrombus formation and degradation and thus risk for arterial thrombosis. We report here results from a genetic analysis of plasma t-PA and PAI-1 levels in a large population-based sample from the PREVEND study in Groningen, the Netherlands (n = 2,527). We measured polymorphisms from genes of the fibrinolytic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.