Article
Drosophila long-term memory formation involves regulation of cathepsin activity.
Nature - 22 Jul 2004
Comas Daniel, Petit Florian, Preat Thomas
Abstract excerpt
Whereas short-term memory lasts from minutes to hours, long-term memory (LTM) can last for days or even an entire lifetime. LTM generally forms after spaced repeated training sessions and involves the regulation of gene expression, thereby implicating transcription factors in the initial steps of LTM establishment. However, the direct participation of effector genes in memory formation has been rarely documented,...
Topics
- Animals
- Cathepsins
- Drosophila Proteins
- Drosophila melanogaster
- Enzyme Inhibitors
- Gene Expression Profiling
- Gene Expression Regulation
- Humans
- Liver
- Memory
- Mutation
- Neuroglia
