Article
The staufen/pumilio pathway is involved in Drosophila long-term memory.
Current biology : CB - 18 Feb 2003
Dubnau Josh, Chiang Ann-Shyn, Grady Lori, Barditch Jody, Gossweiler Scott, McNeil John, Smith Patrick, Buldoc Francois, Scott Rod, Certa Uli, Broger Clemens, Tully Tim
Abstract excerpt
BACKGROUND: Memory formation after olfactory learning in Drosophila displays behavioral and molecular properties similar to those of other species. Particularly, long-term memory requires CREB-dependent transcription, suggesting the regulation of "downstream" genes. At the cellular level, long-lasting synaptic plasticity in many species also appears to depend on CREB-mediated gene transcription and subsequent...
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