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The Histone Deacetylase HDAC4 Regulates Long-Term Memory in Drosophila

9 Dec 2013

Abstract excerpt

A growing body of research indicates that pharmacological inhibition of histone deacetylases (HDACs) correlates with enhancement of long-term memory and current research is concentrated on determining the roles that individual HDACs play in cognitive function. Here, we investigate the role of HDAC4 in long-term memory formation in Drosophila. We show that overexpression of HDAC4 in the adult mushroom body, an...

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PMID: 24349558
DOI: 10.1371/journal.pone.0083903

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