Article
Debra, a protein mediating lysosomal degradation, is required for long-term memory in Drosophila.
PloS one - 1 Jan 2011
Kottler Benjamin, Lampin-Saint-Amaux Aurélie, Comas Daniel, Preat Thomas, Goguel Valérie
Abstract excerpt
A central goal of neuroscience is to understand how neural circuits encode memory and guide behavior changes. Many of the molecular mechanisms underlying memory are conserved from flies to mammals, and Drosophila has been used extensively to study memory processes. To identify new genes involved in long-term memory, we screened Drosophila enhancer-trap P(Gal4) lines showing Gal4 expression in the mushroom bodies,...
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