Article
Consolidation and maintenance of long-term memory involve dual functions of the developmental regulator Apterous in clock neurons and mushroom bodies in the Drosophila brain.
PLoS biology - 1 Dec 2021
Inami Show, Sato Tomohito, Kurata Yuto, Suzuki Yuki, Kitamoto Toshihiro, Sakai Takaomi
Abstract excerpt
Memory is initially labile but can be consolidated into stable long-term memory (LTM) that is stored in the brain for extended periods. Despite recent progress, the molecular and cellular mechanisms underlying the intriguing neurobiological processes of LTM remain incompletely understood. Using the Drosophila courtship conditioning assay as a memory paradigm, here, we show that the LIM homeodomain (LIM-HD)...
Topics
- Animals
- Biological Clocks
- Brain
- Drosophila Proteins
- Drosophila melanogaster
- Heterozygote
- LIM-Homeodomain Proteins
- Memory Consolidation
- Memory, Long-Term
- Models, Biological