Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toll-like receptor 6 gene (TLR6): single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma.

Genes and immunity - 1 Aug 2004

Tantisira K, Klimecki W T, Lazarus R, Palmer L J, Raby B A, Kwiatkowski D J, Silverman E, Vercelli D, Martinez F D, Weiss S T

Abstract excerpt

Toll-like receptor 6 (TLR6) is one of a series of highly conserved innate immune receptors. We resequenced TLR6 in DNA samples from 24 African Americans, 23 European Americans, and 24 Hispanic Americans, identifying 53 SNPs, 22 with an allele frequency >5%. Significant differences in SNP frequencies among the three populations were noted. In all, 11 SNPs caused amino-acid changes, including one with a frequency...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to Asthma and respiratory diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to TLR6 gene

Share to Membrane Glycoproteins

Share to Polymorphism, Single Nucleotide

Share to Receptors, Cell Surface

Share to Toll-Like Receptor 6

Source

Identifiers

PMID: 15266299
DOI: 10.1038/sj.gene.6364096

Genes

TLR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toll-like receptor 6 gene (TLR6): single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma.PMID 15266299Read ↗

Functional characterization of naturally occurring genetic variants in the human TLR1-2-6 gene family.Semantic proximity Read ↗

Toll-like receptor heterodimer variants protect from childhood asthma.Semantic proximity Read ↗

Evaluation of the toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease.Semantic proximity Read ↗

The role of Toll-like receptors and related receptors of the innate immune system in asthmaSemantic proximity Read ↗

Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies.Semantic proximity Read ↗

Toll-like receptor polymorphisms, inflammatory and infectious diseases, allergies, and cancer.Semantic proximity Read ↗

Association of Toll-like receptors 4 (TLR-4) gene expression and polymorphisms in patients with severe asthma.Semantic proximity Read ↗

Association of TLR1, TLR2, TLR4, TLR6, and TIRAP polymorphisms with disease susceptibility.Semantic proximity Read ↗

Polymorphisms in the toll-like receptor 2 subfamily and risk of asthma: a case-control analysis in a Chinese population.Semantic proximity Read ↗

TLR4 polymorphisms and disease susceptibility.Semantic proximity Read ↗

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious diseases.Semantic proximity Read ↗

Single nucleotide polymorphisms in toll-like receptor 6 are associated with altered lipopeptide- and mycobacteria-induced interleukin-6 secretion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.