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Article

Association of Toll-like receptors 4 (TLR-4) gene expression and polymorphisms in patients with severe asthma.

Journal of medicine and life - 1 Jan 2000

Shukur Wasan, Alyaqubi Kifah, Dosh Rasha, Al-Ameri Ali, Al-Aubaidy Hayder, Al-Maliki Rehab, Aridhee Ali, Al-Fatlawi Rawaa, Hadi Najah

Abstract excerpt

Innate immunity plays a central role in the pathogenesis of severe asthma, and it is closely linked to elevated IgE and Toll-like receptor 4 (TLR-4) levels. However, there is a scarcity of information about the association of the TLR-4 receptor polymorphism in the pathogenesis of severe asthma. This study highlights the level of gene expression of different alleles in asthmatic patients compared to healthy...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34621380
DOI: 10.25122/jml-2021-0173
PMCID: PMC8485369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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