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Article

Conformational epitope mapping of antibodies against desmoglein 3 in experimental murine pemphigus vulgaris.

Journal of dermatological science - 1 Aug 2004

Anzai Hidemi, Fujii Yoshiko, Nishifuji Koji, Aoki-Ota Miyo, Ota Takayuki, Amagai Masayuki, Nishikawa Takeji

Abstract excerpt

BACKGROUND: Pemphigus vulgaris (PV) is a blistering skin disease caused by IgG autoantibodies against desmoglein 3 (Dsg3). We have recently developed an active disease mouse model for PV by adoptive transfer of splenocytes from immunized or naive Dsg3-/- mice into Rag2-/- recipient mice. OBJECTIVE: In this study, we characterized the conformational epitopes of anti-Dsg3 IgG antibodies and their pathogenic...

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Source

Identifiers

PMID: 15265525
DOI: 10.1016/j.jdermsci.2004.03.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Conformational epitope mapping of antibodies against desmoglein 3 in experimental murine pemphigus vulgaris.PMID 15265525Read ↗

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