Article
Immune response in pemphigus and beyond: progresses and emerging concepts.
Seminars in immunopathology - 1 Jan 2016
Di Zenzo Giovanni, Amber Kyle T, Sayar Beyza S, Müller Eliane J, Borradori Luca
Abstract excerpt
Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are two severe autoimmune bullous diseases of the mucosae and/or skin associated with autoantibodies directed against desmoglein (Dsg) 3 and/or Dsg1. These two desmosomal cadherins, typifying stratified epithelia, are components of cell adhesion complexes called desmosomes and represent extra-desmosomal adhesion receptors. We herein review the advances in our...
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