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Article

New separation-free assay technique for SNPs using two-photon excitation fluorometry.

Nucleic acids research - 19 Jul 2004

Vaarno Jonne, Ylikoski Emmi, Meltola Niko J, Soini Juhani T, Hänninen Pekka, Lahesmaa Riitta, Soini Aleksi E

Abstract excerpt

A new separation-free method for detection of single nucleotide polymorphisms (SNPs) is described. The method is based on the single base extension principle, fluorescently labeled dideoxy nucleotides and two-photon fluorescence excitation technology, known as ArcDia trade mark TPX technology. In this assay technique, template-directed single base extension is carried out for primers which have been immobilized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15263064
DOI: 10.1093/nar/gnh102
PMCID: PMC506825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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