Article
Mutational analysis of the macrophage scavenger receptor 1 (MSR1) gene in primary lung cancer.
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi - 1 Apr 2004
Yoshimura Akinobu, Gemma Akihiko, Kataoka Kiyoko, Hosoya Yoko, Noro Rintaroh, Seike Masahiro, Kokubo Yutaka, Watanabe Masatoshi, Kudoh Shoji
Abstract excerpt
Allelic deletion at chromosome 8p21-25 is an early and frequent event in the carcinogenesis and development of various cancers. To facilitate investigation of alterations of the macrophage scavenger receptor 1 (MSR1), which is located on 8p22, and to determine the role of this gene in human carcinogenesis and tumor progression, we determined intronic primers designed to amplify the coding region. Since frequent...
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