Article
Class A scavenger receptor deficiency exacerbates lung tumorigenesis by cultivating a procarcinogenic microenvironment in humans and mice.
American journal of respiratory and critical care medicine - 15 Oct 2012
Ben Jingjing, Jin Guangfu, Zhang Yan, Ma Bingqing, Bai Hui, Chen Jiaping, Zhang Hanze, Gong Qixing, Zhou Xiaodan, Zhang Hanwen, Qian Lingling, Zhu Xudong, Li Xiaoyu, Yang Qing, Hu Zhibin, Xu Yong, Shen Hongbing, Chen Qi
Abstract excerpt
RATIONALE: Genetic alterations on 8p22 have been implicated in multiple cancers, including lung cancer. In this region, genetic variants of the class A scavenger receptor (SR-A) gene have been associated with prostate cancer risk and have been highlighted as a potential susceptibility gene of can...
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