Article
A conserved sequence in the mouse variable T cell receptor alpha recombination signal sequence 23-bp spacer can affect recombination.
European journal of immunology - 1 Aug 2004
Probst Jochen, Blumenthal Sibylle G, Tenzer Stefan, Weinschenk Toni, Dittmer Jürgen, Schoor Oliver, Six Adrien, Rammensee Hans-Georg, Pascolo Steve
Abstract excerpt
Although the V-gene segments coding for the TCR alpha and delta chains are mixed together in the alpha delta locus and are recombined by the same processes, some gene segments (TRAV) are rearranged only with TCR Jalpha gene segments, some (TRDV) only with TCR Ddelta gene segments and some (TRADV) with both. To date, no molecular signal is known that can characterize these three different types of gene segments....
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