Article
The Role of Mitochondria in Carcinogenesis.
International journal of molecular sciences - 12 May 2021
Kozakiewicz Paulina, Grzybowska-Szatkowska Ludmiła, Ciesielka Marzanna, Rzymowska Jolanta
Abstract excerpt
The mitochondria are essential for normal cell functioning. Changes in mitochondrial DNA (mtDNA) may affect the occurrence of some chronic diseases and cancer. This process is complex and not entirely understood. The assignment to a particular mitochondrial haplogroup may be a factor that either contributes to cancer development or reduces its likelihood. Mutations in mtDNA occurring via an increase in reactive...
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