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Article

The ArfGAP Glo3 is required for the generation of COPI vesicles.

Molecular biology of the cell - 1 Sept 2004

Lewis Stephen M, Poon Pak Phi, Singer Richard A, Johnston Gerald C, Spang Anne

Abstract excerpt

The small GTPase Arf and coatomer (COPI) are required for the generation of retrograde transport vesicles. Arf activity is regulated by guanine exchange factors (ArfGEF) and GTPase-activating proteins (ArfGAPs). The ArfGAPs Gcs1 and Glo3 provide essential overlapping function for retrograde vesicular transport from the Golgi to the endoplasmic reticulum. We have identified Glo3 as a component of COPI vesicles....

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Identifiers

PMID: 15254269
DOI: 10.1091/mbc.e04-04-0316
PMCID: PMC515341

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The ArfGAP Glo3 is required for the generation of COPI vesicles.PMID 15254269Read ↗

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COPI vesicles accumulating in the presence of a GTP restricted arf1 mutant are depleted of anterograde and retrograde cargo.Semantic proximity Read ↗

Sequential coupling between COPII and COPI vesicle coats in endoplasmic reticulum to Golgi transport.Semantic proximity Read ↗

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