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Article

ARF is required for maintenance of yeast Golgi and endosome structure and function.

Molecular biology of the cell - 1 Mar 1998

Gaynor E C, Chen C Y, Emr S D, Graham T R

Abstract excerpt

ADP ribosylation factor (ARF) is thought to play a critical role in recruiting coatomer (COPI) to Golgi membranes to drive transport vesicle budding. Yeast strains harboring mutant COPI proteins exhibit defects in retrograde Golgi to endoplasmic reticulum protein transport and striking cargo-selective defects in anterograde endoplasmic reticulum to Golgi protein transport. To determine whether arf mutants exhibit...

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Identifiers

PMID: 9487133
DOI: 10.1091/mbc.9.3.653
PMCID: PMC25294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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ARF is required for maintenance of yeast Golgi and endosome structure and function.PMID 9487133Read ↗

Mutations in a highly conserved region of the Arf1p activator GEA2 block anterograde Golgi transport but not COPI recruitment to membranes.Semantic proximity Read ↗

The ARF exchange factors Gea1p and Gea2p regulate Golgi structure and function in yeast.Semantic proximity Read ↗

ARFGAP1 plays a central role in coupling COPI cargo sorting with vesicle formation.Semantic proximity Read ↗

COPI vesicles accumulating in the presence of a GTP restricted arf1 mutant are depleted of anterograde and retrograde cargo.Semantic proximity Read ↗

A role for ADP ribosylation factor in the control of cargo uptake during COPI-coated vesicle biogenesis.Semantic proximity Read ↗

COPI is essential for Golgi cisternal maturation and dynamics.Semantic proximity Read ↗

Golgi enlargement in Arf-depleted yeast cells is due to altered dynamics of cisternal maturation.Semantic proximity Read ↗

Sec7p directs the transitions required for yeast Golgi biogenesis.Semantic proximity Read ↗

The role of ARF1 and rab GTPases in polarization of the Golgi stack.Semantic proximity Read ↗

The ArfGAP Glo3 is required for the generation of COPI vesicles.Semantic proximity Read ↗

Retrograde transport from the yeast Golgi is mediated by two ARF GAP proteins with overlapping function.Semantic proximity Read ↗

The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus.Semantic proximity Read ↗

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