Article
ARF is required for maintenance of yeast Golgi and endosome structure and function.
Molecular biology of the cell - 1 Mar 1998
Gaynor E C, Chen C Y, Emr S D, Graham T R
Abstract excerpt
ADP ribosylation factor (ARF) is thought to play a critical role in recruiting coatomer (COPI) to Golgi membranes to drive transport vesicle budding. Yeast strains harboring mutant COPI proteins exhibit defects in retrograde Golgi to endoplasmic reticulum protein transport and striking cargo-sele...
Topics
- ADP-Ribosylation Factors
- Amino Acid Sequence
- Biological Transport, Active
- Cell Compartmentation
- Coatomer Protein
- Endocytosis
- Endosomes
- Fluorescent Antibody Technique
- Fungal Proteins
- GTP-Binding Proteins
- Golgi Apparatus
- Kinetics
- Membrane Proteins
- Microscopy, Electron
- Mutation
- Saccharomyces cerevisiae
- Staining and Labeling